Expression of co-stimulatory factor B7-2 on the intrahepatic bile ducts in primary biliary cirrhosis and primary sclerosing cholangitis: an immunohistochemical study

1998 ◽  
Vol 186 (2) ◽  
pp. 126-130 ◽  
Author(s):  
Koichi Tsuneyama ◽  
Kenichi Harada ◽  
Mitsue Yasoshima ◽  
Kyosuke Kaji ◽  
M. Eric Gershwin ◽  
...  
1999 ◽  
Vol 52 (10) ◽  
pp. 730-734 ◽  
Author(s):  
S. M. Cruickshank ◽  
J. Southgate ◽  
J. I. Wyatt ◽  
P. J. Selby ◽  
L. K. Trejdosiewicz

1999 ◽  
Vol 54 (5) ◽  
pp. 165-168 ◽  
Author(s):  
Bruno Cupertino Migueletto ◽  
Abrahão Elias Hallack Neto ◽  
Elaine Zamora Domingues ◽  
Pedro Paulo Neves de Castro ◽  
Hartmut Stocker ◽  
...  

Primary biliary cirrhosis (PBC) is a cholestatic liver disease, which is characterized by a chronic inflammatory destruction of intrahepatic bile ducts. It is a rare disorder whose precise etiology is still to be elucidated. Even though the liver is the principal target of PBC, other organ systems also might be affected. Muscular involvement has rarely been described in this disease, and in the majority of cases, muscular weakness has been interpreted as polymyositis. We report the case of a 48-year-old woman suffering from classic PBC, in association with a myopathy whose histological features are distinct from the cases reported before. We also performed a MEDLINE research for PBC and concomitant muscular diseases.


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